Injuries have a cumulative effect on the players left standing. Players feel that they have to make up for the performance of the lost starters and they press, both mentally and physically.
Hopefully the brass has Yabs and Nader and Kadeem Allen and Bird (if and when healthy) come up to the parent club and help chew up some minutes, so the guys left standing don't get hurt and/or wear down and so they don't get cooked later.
Theis (season)and Smart (who knows how long) gone.
Better be careful with Horford, jaylen and Kyrie.
I'd start Baynes, Morris, Tatum, Rozier and Larkin.
2nd unit: Moose, Yabs, Nader, Semi, Allen
Gotta go with what ya got. But, Don't burn Kyrie, Horford, Jaylen....sit them for as long need be.