I might get a lot of flack for this but I'd argue Vince Wilfork is an athletic freak for his weight which is like 350.
You will get no flack from me on that.
Not only was Vince insanely fast exploding off a stance for such a huge guy, he also was in great aerobic shape. Think about what kind of endurance it takes for a 350 lb man to play pretty much every defensive snap in an NFL game in the Miami heat in September. He did that year in and year out for ages.