It's pretty much 50/50, but I say yes. I think he's more likely to go somewhere else than stay there if they don't get to at least the conference finals this year. And as strong as the West is this year with SAS, LAC, HOU, and the GSW, I'm not sure if I see an injury-prone OKC squad making it that far.
It is a double-edged sword, though. If you shop him around for the highest price, then the media gets a hold of it, and he's almost assuredly gone. However, I think you could at least get a good enough price on the former MVP to justify trading him. It does leave the question about what to do with Russ and Ibaka, though. I don't think they should do a total rebuild, but how do you reload after trading last year's MVP? Would a package around Nene, Beal, Oubre, and picks for Durant be enough? What about Butler, Gibson, and picks for Durant? That might be a decent haul for both teams.