I would prefer the #2 seed. First, it gives us home court. That's important not only because of the competitive advantage that it provides, but also because home games provide a significant amount of revenue to the team, which may lead to the team being more aggressive in free agency (or at least retaining its own players).
Additionally, while I'd probably rather play Philly than Detroit, Philly is the type of athletic / running team that can give us trouble. Additionally, there's no guarantee that Philly ends up with the #6 seed; they could easily move up to #5, leaving us with D. Wade in the first round.
All things considered, I'd prefer the #2 seed. However, Orlando is healthier down the stretch, and I'd rather give our players the time they need to rest than to go all out for victories.